Mécanismes physiologiques de la peau sensible

Physiological mechanisms of sensitive skin

Physiological mechanisms of sensitive skin

Discover the characteristics of sensitive skin to better understand your skin's needs.


The pathophysiological mechanisms underlying “sensitive skin” are not yet completely understood. However, the following elements are probably involved in the appearance of this 1234 syndrome:

An alteration of the skin barrier

A reduction in the skin’s tolerance threshold

Nervous sensitivity

DID YOU KNOW ?

Skin sensitivity can be caused or aggravated by numerous exogenous and endogenous factors: Pollution, temperature variations, unsuitable cosmetics, consumption of stimulants, stress, fatigue, etc.

FOCUS ON THE ORIGINS OF SKIN SENSITIVITY

skin diagram Physiological mechanisms Dermina

FOCUS ON THE ORIGINS OF SKIN SENSITIVITY

Alteration of the skin barrier due to water loss and lipid modification

In the stratum corneum, water molecules attach to hygroscopic and water-soluble intracellular molecules called " Natural hydration factor » or NMF which have a strong osmotic potential thus attracting water molecules. They are contained in corneocytes, cells of the upper layer of the epidermis called the stratum corneum. The components of MNF are mainly amino acids, pyrrolidone carboxylic acid, lactic acid, urea, glucose and mineral ions.

The skin's natural flow of hydration rises from the deepest layers to the surface. This flow is possible thanks to aquaporins which selectively conduct water molecules inside and outside cells, while preventing the passage of ions and other solutes. Also known as water molecule channels, aquaporins are membrane proteins that form “ pores ".

Skin hydration is also regulated by the selective permeability of the stratum corneum and the hydrolipidic film together forming the skin barrier. It limits insensible water loss and protects the skin from the entry of irritants. Its permeability depends on the integrity and nature of the lipids between the corneocytes also called intercellular cement.

Any change in this balance can result in an alteration of the skin barrier causing water loss and abnormal penetration of irritants.

Reduction of the skin's tolerance threshold inducing excessive synthesis of pro-inflammatory cytokines


Sensitive skin will react to irritants and external factors that have no effect on normal skin. This sensitivity results in excessive synthesis of pro-inflammatory cytokines which have the role of activating the inflammation process.

Nervous sensitivity


Human skin has many sensory nerve fibers reaching the bottom of the epidermis. They are what allow the central nervous system to know the condition of the skin and to react to different chemical, thermal and physiological stimuli. An exaggeration of the nervous response and a low activation threshold are involved in the phenomenon of skin sensitivity.

In summary…



The best way to minimize signs of skin sensitivity is to reduce inflammation with soothing ingredients. In addition, the skin barrier must be strengthened by providing lipids and hydration to the skin. This will limit the entry of elements that could stimulate inflammation or nerve response. This is why a suitable cosmetic routine can help reduce the signs of sensitivity.

DISCOVER THE RIGHT ROUTINE

1 Progress in dermato-allergology Grenoble 2005
2 Sensitive skin: An overview Arun C Inamadar, Aparna Palit Department of Dermatology, SBMP Medical College, BLDE University, Bijapur, India
3 The Sensitive Skin Syndrome Hadar Lev-Tov and Howard I Maibach1 Indian J Dermatol. 2012 Nov-Dec; 57(6): 419–423.
4 Sensitive skin: an overview E. Berardesca, M. Farage and H. Maibach International journal of cosmetic science vol35 number 1 February 2013

BACK TO ARTICLES

Expertise peau

Newer Post →

The Mag

RSS
Comment recharger les batteries de ma peau en hiver ?
Rituel belle peau

How do I recharge my skin's batteries in winter?

By Emilie Berger

The cold is fast approaching and we can already feel our skin sending us signals: it's time to take out our cold weather gear! Because...

Read more
Préparez votre peau pour les fêtes de fin d’année !
Astuces du quotidien

Prepare your skin for the end-of-year holidays!

By Emilie Berger

During this very special period, the end of year celebrations arrive like a ray of sunshine. So for sure, this year, we will be beaming...

Read more